|
Publications/Presentations
The MicroArray Quality Control (MAQC) Project Shows Interplatform Reproducibility of Gene Expression Measurements
Publication: Nat Biotechnol. 2006 Sep;24(9):1151-61)
Authors: Shi L, Reid LH, Jones WD, Shippy R, Warrington JA, Baker SC, Collins PJ, de Longueville F, Kawasaki ES, Lee KY, Luo Y, Sun YA, Willey JM, Setterquist RA, Fischer GM, Tong W, Dragan YP, Dix DJ, Frueh FW, Goodsaid FM, Herman D, Jensen RV, Johnson CD, Lobenhofer EK, Puri RK, Schrf U, Thierry-Mieg J, Wang C, Wilson M, Wolber PK, Zhang L, Slikker W Jr, Shi L, Reid LH; MAQC Consortium.
Rat Toxicogenomic Study Reveals Analytical Consistency Across Microarray Platforms
Publication: Nat Biotechnol. 2006 Sep;24(9):1162-9. Links
Authors: Guo L, Lobenhofer EK, Wang C, Shippy R, Harris SC, Zhang L, Mei N, Chen T, Herman D, Goodsaid FM, Hurban P, Phillips KL, Xu J, Deng X, Sun YA, Tong W, Dragan YP, Shi L.
Performance Comparison of One-Color and Two-Color Platforms Within the Microarray Quality Control (MAQC) Project
Publication: Nat Biotechnol. 2006 Sep;24(9):1140-50
Authors: Patterson TA, Lobenhofer EK, Fulmer-Smentek SB, Collins PJ, Chu TM, Bao W, Fang H, Kawasaki ES, Hager J, Tikhonova IR, Walker SJ, Zhang L, Hurban P, de Longueville F, Fuscoe JC, Tong W, Shi L, Wolfinger RD
The Pro12Ala Variant of the PPARG Gene is a Risk Factor for Peroxisome Proliferator-Activated Receptor-Gamma/Alpha Agonist-Induced Edema in Type 2 Diabetic Patients
Publication: J Clin Endocrinol Metab. 2006 Sep;91(9):3446-50
Authors: Hansen L, Ekstrøm CT, Tabanera Y Palacios R, Anant M, Wassermann K, Reinhardt RR
Biomarkers of Liver Injury
Biomarkers Track Featured Presentation, Drug Discovery Technology 2006 (Boston, MA; 8/9/06)
Author: Higgins, A.
Profiles of Global Gene Expression in Ionizing-Radiation-Damaged HumanDiploid Fibroblasts Reveal Synchronization Behind the G1 Checkpoint in a G0-like State of Quiescence
Publication: Environ Health Perspect. 2006 Apr;114(4):553-9.
Authors: Zhou T, Chou JW, Simpson DA, Zhou Y, Mullen TE, Medeiros M, Bushel PR, Paules RS, Yang X, Hurban P, Lobenhofer EK, Kaufmann WK.
Metabolomic Analysis of Alchohol Toxicity in Rat Liver and Serum
03/06/2006
Authors: Imran Shah, Ivan Rusyn, John Cai, Akira Maki, Daniel Kim, Liya Qin, Jayme Corbell, Courtney Woods, Fulton Crews, Alan Higgins
Abstract: Chronic intake of ethanol is known to induce significant toxicity in various organs. Liver and brain are two of the main targets. These studies were conducted to test the hypothesis that metabolomic analysis can distinguish ethanol consumption from other caloric sources and to provide insight into the mechanisms and/or markers of organ damage.
Temporal Correlation of Pathology and DNA Damage With Gene Expression in a Choline-Deficient Model of Rat Liver Injury
Publication: Hepatology. 2005 Nov;42(5):1137-47.
Authors: Boorman GA, Blackshear PE, Parker JS, Lobenhofer EK, Malarkey DE, Vallant MK, Gerken DK, Irwin RD.
Hepatic Gene Expression Changes Throughout the Day in the Fischer Rat: Implications for Toxicogenomic Experiments
Publication: Toxicol Sci. 2005 Jul;86(1):185-93. Epub 2005 Apr 6.
Authors: Boorman GA, Blackshear PE, Parker JS, Lobenhofer EK, Malarkey DE, Vallant MK, Gerken DK, Irwin RD.
Standardizing Global Gene Expression Analysis Between Laboratories and Across Platforms
Publication: Nature Methods. vol. 2, no. 5, May 2005, p.351
Authors: Members of the Toxicogenomics Research Consortium
Transcriptional Profiling of the Left and Median Liver Lobes of Male F344/N Rats Following Exposure to Acetaminophen
Publication: Toxicologic Pathology, 33:111-117, 2005
Authors: Irwin RD, Parker JS, Lobenhofer EK, Burka LT, Blackshear PE, Vallant MK, Lebetkin EH, Gerken DF, Boorman GA.
Variation in the Hepatic Gene Expression in Individual Male Fischer Rats
Publication: Toxicol Pathology. 2005;33(1):102-10.
Authors: Boorman GA, Irwin RD, Vallant MK, Gerken DK, Lobenhofer EK, Hejtmancik MR, Hurban P, Brys AM, Travlos GS, Parker JS, Portier CJ.
MicroRNA Expression Detected by Oligonucleotide Microarrays: System Establishment and Expression Profiling in Human Tissues
Publication: Genome Res. 2004 Dec;14(12):2486-94
Authors: Barad O, Meiri E, Avniel A, Aharonov R, Barzilai A, Bentwich I, Einav U, Gilad S, Hurban P, Karov Y, Lobenhofer EK, Sharon E, Shiboleth YM, Shtutman M, Bentwich Z, Einat P.
Toward an Integrative Systems Toxicology
Publication: Pharmacogenomics. 2004 Dec;5(8):1163-6.
Authors: Patrick Hurban, Ph.D.
Precise Phenotypic Anchoring for Drug Target Identification, Validation and Biomarker Discovery Using an Advanced Systems Biology Approach
Publication: Drug Discovery World Summer 2004
Authors: Dr. Peter C. Johnson & Dr. Alan J. Higgins
|
|
